Whether the administrative division adjustment is reasonable is not only directly related to the allocation of social and natural resources, but also to economic development and social stabilityin a region. A scientific approach to analyze the reasonableness of zoning adjustment is of enormous importance. However, the current regional administrative division adjustment in Nanjingis dominatedby qualitative evaluation methods and empirical judgmentas well as a lack of effective quantitative analysis, which has resulted in uncertainty in the analysis process. Therefore, based on geographic information system (GIS) technology, Nanjing's administration adjustments calculated from the hinterland model were compared with the actual adjustments since 1995. Next, the rationality of Nanjing's administrative division adjustmentwas evaluated. The evaluation results showed that the administrative division adjustment was consistent with the results calculated from the hinterland model, which illustrates the rationality of the actual adjustments. However, it is worth noting thatadministrative divisionproblems concern superstructure, in addition totheeconomic level, geographical scope, and populationsize of the area, which are alsoclosely related to political, cultural, historical, and other factors. Itcannot completely relyon the results ofquantitative analysis. The specificneedsofthe township should be consideredin a subsequentstudy.