In order to increase the effective area of image sensor and to avoid the interruption of communications in optical camera communications (OCC),a novel non-line-of-sight (NLOS) OCC scheme is proposed,which uses a high-resolution image sensor to receive completely a data packet within a single frame.The NLOS channel profits the mitigation of the blooming effect from the optical source,and also the increment of effective area of an image sensor for communications.Furthermore,the high-accuracy synchronization scheme has been adopted for the integration of multiple pixel columns to mitigate the signal loss in an NLOS channel.High-resolution image sensor has been applied for fast signal variation,as well as the increment of both synchronization accuracy and the data rate.The performances of OCC system with the data rate of 2.15 kpbs and a link range of 1.5 m has been verified experimentally.It has shown that a data packet of 16 bits could be reliably received within a single frame,which is applicable for indoor positioning and navigation,photonics labeling,and so on.