The tobacco field experiment data of Yuxi and Zhaotong during 2010-2011 were used tosimulate the potential growth processes of tobacco in Yunnan province,thus calibrate and validate the WOFOST model for tobacco development.The tobacco field experiment data of Zhaotong in 2010 were applied to the WOFOST model to get the localized WOFOST model parameters for Yunnan province,which were then validated by the rest of the experimental data.The results show that the WOFOST model can simulate the tobacco potential growth process,and the current tobacco yield is only about 88% of its potential yield,thus there's still room for increasing tobacco yield in Yunnan province.