The high-precise measurement of temperature is always the important technology of automatic weather station (AWS) design.Multiplexer CD4052 is widely used in data acquisition unit (DAU) design,which is a most important part of AWS.Until now,there is still a lack in research on the impact of offset current and temperature characteristics of CD4052 in temperature measurement.This paper focuses on the impact of CD4052 offset current for temperature measurement.Study results show that the offset current has important influence on temperature measurement error,and the error is significantly correlated with environmental temperature.The results are valuable in theoretical basis and engineering application for design and offset of DAU.