Net Primary Productivity (NPP) is the accumulation of organic matter by green plants per unit of space and time.Using Geographic Information System and Remote Sensing spatial analysis software,this paper analyzes the spatio-temporal distribution characteristics of vegetation NPP in Jiangsu province from 2000 to 2006 based on NPP data from EOS／MODIS.Results show a decreasing spatial trend from southeast to northwest and a temporal trend with higher NPP in 2004.The average annual NPP in Jiangsu province (569.28 gC／(m²·a)) was higher than the national average NPP during the same period (345.91 gC／(m²·a)) and a little lower than the average NPP in Guangdong(595.51 gC／(m²·a)).Analyzing NPP of different city and different buffer of shoreline shows that the NPP increases firstly and then decreases with the increasing distance to shoreline.NPP of Nantong (a city in the Southeast of Jiangsu) was highest (693.57 gC／(m²·a)),while NPP of Xuzhou (a city in the Northwest of Jiangsu) was lowest (478.72 gC／(m²·a)).NPP grows to the highest when the distance to the Ring Buffer increases to 30 km,and land cover change is an influential factor affecting changes in vegetation NPP based on Ring Buffer.Analysis of vegetation NPP shows that climate factors were the key factors controlling the NPP in Jiangsu,and the human influence is becoming more and more important.