The 1-butyl-3-methylimidazolium glycine acid salt([bmim]Gly) was prepared by two steps.The first step,the intermediary,1-butyl-3-methylimidazolium hydroxide ([bmim]OH) was prepared by 1-butyl-3-methyl imidazolium bromide ([bmim]Br) through a static anion ion exchange.The optimum reaction conditions were obtained by single factor experiments.The second step,the [bmim]OH and glycine were mixed and reacted,then were dried under vacuum and washed with methanol,to form high purity product.The structure of product was confirmed and characterized by ¹H NMR and IR.Compared with dynamic preparation method,the proposed static method is simple in operation and rapid in production rate,and consumes less leaching water and energy,so it promotes the preparation of the amino acid ionic liquid in a more green and industrialized direction.